Journal of Oral Implantology Evaluation of vertical bone regeneration using block and particulate forms of Bio-Oss® bone graft. A histological study in rabbit mandible

Abstract: The aim of the present study was to evaluate histologically vertical bone regeneration outcomes after using bovine bone graft material in block and granular forms. The buccal bony plates of the outer mandibles of ten New Zealand rabbits received BioOss® blocks that were immobilized using orthopedic mini-plates and other ten received granular forms that was gently packed and stabilized into the custom-made perforated metallic cubes. The mean graft area (GA), new bone area (NBA), bone-tograft contact (BGC) and the maximum vertical height reached by the new bone development (MVH) were histometrically evaluated and showed no significant differences between two graft types. The new bone was observed mostly close to the basal bone, and developed penetrating the trabecular scaffold in the form of seams that covered the intra-lumen surfaces of the block type graft while in the granular graft type the new bone was observed to grow between the graft particles usually interconnecting them. Either form of Bio-Oss® was capable of providing considerable vertical bone augmentation.